GOS MAX

GOS increases levels of Bifidobacteria and other beneficial microbials in the gut which can decrease gut discomfort, constipation, and other problems associated with normal GI functions. This is especially important when animals swallow exudate from their nasal cavity during episodes of harmful microbial presence in the nasopharyngeal tissues. The swallowed exudate influences the harmony of the gut microbiome, but the GOS can allow the microbiome to return to a healthy balance of beneficial microorganisms.

GOS MAX ingredients function via the gut-brain axis, improving anxiety levels and supporting overall mental well-being, allowing new solutions that improve both gut and overall health simultaneously, see Figure 1.

Figure 1 GOS MAX can be an important part of the diet of animals that support a healthy gut microbiome.

The gut microbiome is a complicated mystery to many animal owners. In a single animal, there are thousands of organisms in the microbiome. A healthy gut microbiome is essential for an animal’s development, maintenance, and immunity, and plays an integral role in maintaining health.

Gut microbiota can be modified by dietary prebiotics, and at the same time have a role in the bacterial metabolism. Depending on the type of diet administered, the gut microbiota is modified with bacteria species resulting abundantly as a response to dietary composition. GOS MAX can be processed by the gut microbiota supporting their digestion or using GOS MAX as a source of energy for their own metabolism.

Figure 2. Galacto-oligosaccharide structure

GOS reach the large intestine without being broken down by the endogenous enzymes. Because of this they are sugars that are not easily converted into energy by the body. This fact helps good bacteria such as intestinal bifidobacterial to crowd out the bad bacteria.

The main benefits of GOS in Gos Max:

1. Improved Gut Health:

• Inhibition of harmful bacteria growth. ​

• Modulation of gut microflora to improve host health. ​

• Prevention of gastrointestinal (GI) tract infections. ​

2. Enhanced Nutrient Absorption:

• Increased bioavailability of minerals. ​

• Vitamin synthesis. ​

3. Reduced Risk of Diseases:

• Reduced risk of colon cancer. ​

• Reduction in cholesterol and blood lipids. ​

• Prevention of diarrhea, constipation, infections, liver damage, cancer, toxigenesis, and encephalopathy. ​

4. Immune System Support:

• Stimulation of immune function. ​

5. Attenuation of Pathogen Virulence:

• Anti-adhesive effects and competition for receptors. ​

• Reduction in pathogen colonization. ​

6. Bifidogenic Effects:

• Promotion of beneficial bacteria like bifidobacteria. ​

7. Species-Level Changes:

• Potential to stimulate individual species with powerful antimicrobial activity. ​

8. Distal Colon Delivery:

• Targeting the distal colon, which is associated with most gut disorders. ​

9. Low-Dose Effects:

• Effective at low dosages without side effects. ​

10. Defined Health Outcomes:

Multifunctionality, including anti-adhesive and attenuative effects.

Potential benefits of the Colostrum bioactive peptides in GOS MAX:

Colostrum is the elixir of life

•          Truly unique natural secretion produced by the mammary glands at the beginning of lactation

•          Intended for ingestion by the newborn during the first hours of life

•          Without question, the most important meal the newborn will ever consume is its first one.

•          How you start a newborn determines how it will develop, survive, and reach its genetic potential.

Components of Colostrum include:

•          Specific immunoglobulins (IgG, IgM, IgA), which convey passive immunity to the newborn

•          Proteins Transferrin and lactoferrin, which bind iron, an essential growth factors for most aerobic bacteria

•          Enzymes Xanthine Oxidase and Lacto Peroxidase, which have antibacterial activity, particularly in the gut

•          Insulin-like growth promoting hormones, which increase the uptake of glucose and amino acids by cells in the body

•          Thymosin sub-units, which affect the thymus gland, the trigger for the immune system

•          Various cytokines which act on different cells associated with the immune response

•          Proteins like conglutinin, beta-lysin and ubiquitin, whose functions are unknown

Mechanism of absorption is quite simple (newborns):

–         Low enzymatic activity in the gut and inhibitors in the Colostrum let immunoglobulins reach the ileum intact

–         They are absorbed and transported to lymph nodes and into intestinal blood vessels

–         IgG and IgM enter the circulation

–         IgA is re-secreted into the gut

–         Process is very rapid

–         Increase in serum IgG and IgM levels within 24 hours

–         Levels reach the peak at about 48 hours, then decline steadily due to normal break-down process

IgG and IgM protect against septicemia

IgA is primarily a defense against enteric infections acting at the mucosal surface

The spectrum of protection is directly related to the diversity of antibodies in the Colostrum

–         Mother’s exposure to pathogens if suckled, right after birth will transmit her unique immunity components

–         Pool of Colostrum maximizes diversity to various immunity components

–         Desired Colostrum product characteristics

–         Only from first milking Colostrum

–         From a Highly diverse antibody pool

–         Proven to contain biologically active components

–         Guaranteed quantity per package

–         Easy to use

Role of Other Proteins

•          Thymosin sub-units act on the thymus gland and trigger the immune system

•          Cytokines stimulate the development of different cells associated with immune system

•          Lactoferrin and Transferrin act in the gut and bind iron, which impedes the growth of aerobic bacteria like E. coli

•          Combining lactoferrin with specific IgG produces more potent antibacterial effect

•          Enzymes Xanthine Oxidase and LactoPeroxidase inhibit growth of pathogens in the gut

•          Insulin-like growth factors stimulate the uptake of glucose and amino acids by cells in the body

•          Research has shown this property of Colostrum to be useful to athletes and bodybuilders